Toyah Willcox
as
Mad
Graham McTavish
as
Bully
Alice Eve
as
Charlotte Lockton
Jack Davenport
as
Joshua McCullen
Alan Parker
Director
Holland Taylor
as
Claudia van Doren
Richard Belzer
as
M.C.
Barry Miller
as
Ralph
Stan Lee
as
Self
Timothy Dalton
as
Self
Michael Rooker
as
Self
Betsy Brantley
as
Neely Pritt
Christopher Malcolm
as
Vance Parker
John Standing
as
Gordon
Michael Caine
as
Robert Blakeley
Susannah York
as
Stella
Sam Irvin
Director
Scott Atkinson
as
Dr. Bradley Bradley
Mary Scheer
as
Lady Ema Hellsubus
Sam Irvin
as
Nicholai Hellsubus
Matthias Schweighöfer
as
Frankie
Danny Glover
as
Miles
Steve Zahn
as
Pete
Freddie Highmore
as
Justin
Charles Dance
as
Legantir
Antonio Banderas
as
Sir Clorex
Drew Barrymore
as
Danielle
Timothy West
as
King Francis
Judy Parfitt
as
Queen Marie
Lee Arenberg
as
Elwood Gutworthy
Jeremy Irons
as
Profion
Marlon Wayans
as
Snails
Joan Sims
as
Belle Armitage
Peter Butterworth
as
Doc
Andy Bradford
as
Rider
Todd Stashwick
as
Additional Voices
Thomas Brodie-Sangster
as
Ferb Fletcher
Dee Bradley Baker
as
Perry the Platypus / Perry the Platyborg / Additional Voices
Burnell Tucker
as
Airline Co-Pilot
Ornella Muti
as
Princess Aura
Philip Stone
as
Zogi, the High Priest
Ewan McGregor
as
Chris
Timothy Spall
as
Churchill
Rosamund Pike
as
Daisy
Dee Bradley Baker
as
Perry
John O'Hurley
as
Roger Doofenshmirtz
'Weird Al' Yankovic
as
(voice)
Bob Geldof
as
Bob Geldof
George Wendt
as
Film Producer
Hugh Laurie
as
Poirot
Tim Curry
as
Dr. Frank-N-Furter - A Scientist
Susan Sarandon
as
Janet Weiss - A Heroine
Alex Proyas
Director
Kiefer Sutherland
as
Dr. Daniel P. Schreber
Jennifer Connelly
as
Emma Murdoch
Rufus Sewell
as
John Murdoch